Atharva Shetye

Atharva Shetye

I am a Ph.D. researcher in Mechanical Engineering at UCLA and former R&D Design Engineer at BD, with experience spanning medical device development, mechanical design, computational mechanics, and biomedical imaging. My work combines CAD, FEA, experimental mechanics, and advanced image analysis methods to study complex mechanical behavior in biological systems and develop engineering solutions for medical applications.

At BD, I led mechanical design activities across multiple medical device product lines, translating requirements into manufacturable designs through CAD, GD&T, tolerance stack-up analysis, FEA, DFM, testing, and cross functional product development. My doctoral research builds on this engineering foundation through computational modeling, experimental characterization, and image based measurement of ocular tissue mechanics.

I am a named inventor on 8 U.S. patent applications and author of 2 peer reviewed publications. This portfolio highlights selected projects across mechanical design, simulation, experimental mechanics, and computational imaging.

PROFESSIONAL & RESEARCH EXPERIENCE

Work & R&D Experience

UCLA Logo

Doctoral Researcher @ Jules Stein Eye Institute, UCLA

Los Angeles, CA

Aug 2024 – Present
Developed a PyTorch based image analysis pipeline using DeepLabV3+ and RAFT to track tissue deformation induced by eye movements and measure subpixel displacements and Green Lagrangian strains in retinal images.
Built a signal processing workflow to identify cardiac pulse related deformation frequencies in retinal images using FFT and Lomb–Scargle analysis.
Reconstructed anatomically accurate 3D CAD of complex ocular structures in CATIA 3DExperience and currently developing an Abaqus FEA incorporating experimentally derived viscoelastic material parameters to model dynamic loading and rapid saccadic eye movements.
Quantifying time series strain fields via high-speed imaging to derive in vivo retinal viscoelastic properties for future dynamic FEA simulations.
Characterized viscoelastic properties of human ocular tissues using uniaxial tensile stress relaxation testing under controlled physiological conditions.
Implemented a generalized Maxwell model with Prony series fitting to extract instantaneous and equilibrium moduli and relaxation times from experimental data.

PhD Research Projects:

Becton Dickinson (BD) Logo

R&D Design Engineer II @ Becton Dickinson and Company (BD)

Bengaluru, India

Jul 2020 – Aug 2023
Named inventor on 8 U.S. patent applications and contributor to 21 invention disclosures.
Owned end-to-end mechanical design across 9 hypodermic product lines supporting an $80M revenue portfolio.
Redesigned Luer lock and Luer slip taper geometries using SolidWorks, GD&T, tolerance stack-up analysis, and Abaqus FEA; collaborated with 4 manufacturing plants to meet ISO requirements while minimizing tooling modifications through DFM.
Translated system requirements into detailed design outputs, including 3D CAD models, dimensional and tolerance specifications, and product specifications for updated Luer designs.
Led cross functional design risk assessments, root cause investigations to generate ISO 14971 aligned DFMEAs for newly designed components and product changes.
Drove cross functional design reviews and phase-gate approvals across Medical Affairs, Regulatory, Quality, and Manufacturing engineering teams.

BD Key R&D Project:

RESEARCH INITIATIVES

Featured Projects

PROJ-01Ongoing Project
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3D CAD and Dynamic FEA of Ocular Mechanics During Saccades

Developing an anatomically consistent 3D ocular model in CATIA and Abaqus to simulate extraocular muscle activation and quantify transient stress, strain, and deformation during rapid eye movements.

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PROJ-02Completed Project
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Viscoelastic Material Characterization of Human Ocular Tissues

Characterized 6 human ocular tissue regions through tensile stress relaxation testing and generalized Maxwell/Prony-series modeling to derive time dependent material properties.

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PROJ-03Completed Project
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In Vivo Measurement of Gaze Induced Ocular Strain

Developed an image based mechanics pipeline combining deep learning segmentation, image registration, RAFT optical flow, and continuum mechanics to quantify full field ocular strain during gaze shifts.

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PROJ-04Completed Project
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Cardiac Pulse Estimation from Retinal Strain in Sequential cSLO Imaging

Quantified time varying retinal vessel strain from sequential cSLO imaging and used FFT and Lomb–Scargle spectral analysis to identify cardiac pulse related deformation frequencies.

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PROJ-05Ongoing Project
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In Vivo Estimation of Retinal Viscoelastic Relaxation from High-Speed cSLO

Developing a high-speed image analysis workflow to track post saccadic retinal strain decay and non invasively estimate effective viscoelastic relaxation time constants in vivo.

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PROJ-06Completed Project
Becton Dickinson (BD) Logo

BD Hypodermic Luer Redesign & ISO 80369-7 Transition

Redesigned Luer lock and Luer slip interfaces across 9 high volume product lines using SolidWorks, GD&T, tolerance analysis, Abaqus FEA, and DFM while minimizing manufacturing and tooling changes.

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ACADEMIC BACKGROUND

Education & Research Training

UCLA Logo
Jan 2025 – Present

Ph.D. in Mechanical Engineering

University of California, Los Angeles (UCLA)

Los Angeles, CA•GPA 3.90 / 4.00

Focused on studying the mechanical response of ocular tissues during static gaze fixations and dynamic eye movements. Using principles of mechanical engineering, currently working towards tissue property characterization using deep learning based image analysis, dynamic FEA, and experimental tests to quantify real time ocular tissue response under physiological dynamics.

UCLA Logo
Sep 2023 – Jan 2025

M.S. in Mechanical Engineering

University of California, Los Angeles (UCLA)

Los Angeles, CA•GPA 3.90 / 4.00

Specialized in the design of mechanical systems and robotic manipulators. Coursework included compliant mechanisms, and kinematics, dynamics, and control of robotic arms.

NIT Tiruchirappalli Logo
Jul 2016 – May 2020

B.Tech. in Production Engineering

National Institute of Technology, Tiruchirappalli

Tiruchirappalli, India•GPA 3.93 / 4.00

Core production and industrial engineering program focusing on advanced manufacturing processes, CAD/CAM prototyping, operations research, quality control, precision machining, and industrial automation.

PEER-REVIEWED RESEARCH

Journal Publications

Optic Disc and Retinal Strain Due to Vertical Duction

Investigative Ophthalmology & Visual Science (IOVS, September 2026)

Confocal scanning laser ophthalmoscopy (cSLO) and image-based strain analysis were used to evaluate optic disc and peripapillary retinal vessel deformation during vertical versus horizontal ductions. Notably, just 10° of vertical rotation produced strain magnitudes comparable to 30° of horizontal duction, with strain peaking in the optic disc and younger adults exhibiting approximately twofold higher strain than older adults, demonstrating significant optic nerve tethering during vertical gaze shifts.

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Evidence That Cardiac Pulse Strains Retinal Vessels in and near the Optic Disc During Ocular Ductions

Bioengineering Journal (MDPI, June 2026)

Sequential confocal scanning laser ophthalmoscopy (cSLO) images were analyzed to quantify cardiac pulse induced retinal vessel strain and evaluate its variation across different gaze positions. Deep learning segmentation, RAFT optical flow, Green–Lagrangian strain analysis, and spectral methods identified pulse related deformation, with mean equivalent strain ranging from approximately 0.27% to 0.36%, exceeding the 0.16% noise threshold across gaze positions.

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Linear Viscoelasticity of Human Ocular Tissues During Tensile Stress Relaxation

Investigative Ophthalmology & Visual Science (IOVS, May 2026)

Tensile stress relaxation testing was used to characterize the viscoelastic behavior of six human ocular tissue regions and derive region specific material properties for computational modeling. Generalized Maxwell models represented through Prony-series parameters quantified substantial regional differences in stiffness and relaxation behavior, with instantaneous modulus ranging from approximately 3.5 MPa in the optic nerve to 12.6 MPa in the anterior sclera and long term relaxation times ranging from approximately 60 to 460 seconds.

Read Journal Paper ↗
INTELLECTUAL PROPERTY

Patents & Inventions

Disinfecting Cap for Male and Female Needleless Connectors with Clamping Arms

U.S. Patent Application US20240269454A1

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Disinfecting Cap for Male and Female Connectors Including Deformable Housing

U.S. Patent Application US20240245899A1

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Medical Device Kit with Integrated Organization and Waste Disposal Features

U.S. Patent Application US20240139466A1

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Universal Disinfection Device with Rotatable Sleeve

International Patent Application WO2025198953A1

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Universal Fluid Connector Assembly with a Regulating Valve Component

U.S. Patent Application US20240123211A1

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Secondary Securement Device for Vascular Access Device I

U.S. Patent Application US20250082904A1

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Secondary Securement Device for Vascular Access Device II

U.S. Patent Application US20240424261A1

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Secondary Securement Device for Vascular Access Device III

International Patent Application WO2024151251A1

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HONORS & RECOGNITION

Awards & Honors

UCLA Logo
Jun 2026
Graduate Award

Graduate Student Research Excellence Award

Jules Stein Eye Institute · UCLA

Awarded for excellence in biomechanics research, specifically for developing deep learning segmentation and optical flow pipelines to quantify ocular tissue strain and deformation during eye movements.

ARVO Logo
May 2026
ARVO Grant

Retina Research Foundation Travel Grant

Association for Research in Vision and Ophthalmology (ARVO)

Competitive travel grant awarded to present novel research on ocular tissue strain in peripapillary retina due to eye movements at the Association for Research in Vision and Ophthalmology (ARVO) annual conference.

Becton Dickinson (BD) Logo
Jun 2023
Design Excellence

BD "Drive Results" Award for Design Excellence (FY23)

Becton Dickinson (BD)

Awarded for executing key design deliverables related to product launch.

Becton Dickinson (BD) Logo
Nov 2022
Leadership Award

BD "Strong Teams" Award for Cross-Functional Leadership

Becton Dickinson (BD)

Awarded for driving essential cross-functional collaboration to deliver core fiscal-year business objectives.